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TRAMADOL safety information
Tramadol is a mild inducer of selected drug metabolism tramadol overdose toxbase tramadol controlled in missouri tramadol schedule arkansas tramacet pathways measured in animals .
Use tramadol With Cimetidine Concomitant administration of ULTRAM® with cimetidine does not result in clinically significant changes in tramadol pharmacokinetics .
Therefore, no alteration of the tramadol ULTRAM® dosage regimen is recommended .
Use With Digoxin and Warfarin Post-marketing surveillance has revealed rare reports tramadol of digoxin toxicity and alteration of warfarin effect, including elevation of prothrombin times .
Carcinogenesis, Mutagenesis, Impairment of Fertility A slight, but statistically significant, increase in two common murine tumors, pulmonary and hepatic, was observed in a tramadol mouse carcinogenicity study, particularly in aged mice .
Mice were dosed orally up to 30 mg/kg (90 mg/m2 or tramadol 0 . 36 times the maximum daily human dosage of 246 mg/m2) for approximately two years, although tramadol dosage instructions tramadol alcohol bijwerkingen ultram with no perscription and delivered the study was not done with the Maximum Tolerated Dose .
This finding is not believed to suggest risk in tramadol humans .
73 times the maximum daily human does tramadol cause high blood sugar tramadol withdrawal thomas recipe tramadol bluelight tramadol dosage) . No such finding occurred in a rat tramadol 50 mg onset tramadol 50mg tablets street value tramadol hcl break in half tramadol xr side carcinogenicity study (dosing orally up to 30 mg/kg, 180 mg/m2, or 0 .
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